Ponzio began her career as a Lieutenant in the United States' Navy Nurse Corps. After experimenting with various mediums in figurative art, she found her voice in sculpture and made the decision to pursue it. She completed her artistic training at the Florence Academy of Art (FAA) in Florence, Italy, where she completed the Sculpture Program in 2008. She was then the director of the Artistic Anatomy and Ecorche Sculpture programs, as well as a figure drawing instructor, at the FAA until 2011, when she returned to the U.S. and set up her studio in San Francisco. Her figure compositions and portraits have received recognition and honors from several organizations including the Art Renewal Center, the Catharine Lorillard Wolfe Art Club, The Portrait Society of America, The California Art Club and the National Sculpture Society from which Alicia received the Alex J. Ettl Grant in 2016. Her work ranges from miniature portraits to larger scale single figure and multi-figure compositions.